4th European course on Pharmacokinetics and Pharmacodynamics of Protein Therapeutics. November 20-22 2019. Lyon, France Information & Registration Form After a great success of the 3rd edition in November 2018, AP2POP association is organising a 4th European course, November 20-22 2019 in Lyon. This 3-day course will introduce participants to basic principles in the pharmacokinetics and pharmacodynamics of novel therapeutic proteins and provide opportunities for basic hands-on exercises in the PK/PD evaluation of these compounds. Topics include target-mediated drug disposition, tissue and tumor penetration, first-in-human dose selection, immunogenicity, clinical pharmacology challenges, biosimilars, and drug-drug interactions. Hands-on exercises and simulations will be performed individually and in small groups using simple software tools (no prior experience required). The course is a shortened version of the week-long course on « Pharmacokinetics and Pharmacodynamics of Protein Therapeutics – Concepts and Hands-On Modeling and Simulation » that Drs. Meibohm and Gabrielsson have offered for the last nine years in the United States. Christian, Philippe and Emilie are happy to host this course in Lyon.