Pharmacometric Expertise
to Support Your Drug

Build a long-term relationship of trust with us

Streamlining Drug development with Pharmacometrics

At Calvagone, we specialize in providing top-tier pharmacometrics consulting services, dedicated to supporting our clients throughout their drug development process.
Our team is a diverse blend of professionals, each bringing a wealth of experience in areas such as programming, mathematics, pharmacology, pharmacometrics, and drug development.

Understanding Pharmacometrics

Pharmacometrics is defined as the science that quantifies drug, disease and trial information to aid efficient drug development and/or regulatory decisions. Drug models describe the relationship between exposure (or pharmacokinetics), response (or pharmacodynamics) for both desired and undesired effects, and individual patient characteristics. Disease models address the relationship between biomarkers and clinical outcomes, time course of disease and placebo effects. Trial models capture the inclusion/exclusion criteria, patient discontinuation and adherence, and are the central piece of clinical trial simulations.

Our Services

Calvagone provides services in: Data Management, Non-Compartmental Analysis (NCA), population PK and PK/PD Modelling, Simulation and General Consulting to Support Drug Development.

Calvagone can support Pediatric drug development by applying scaling from Adults to Children and support the writing of the Pediatric Investigation Plan (PIP).

We have the expertise to strategize your project from early objective setting up to a concise and understandable reporting of the complex concepts and findings.

We can also provide specific courses and hands-on trainings, such as a basic and advanced NONMEM workshop.

We received Crédit Impôt Recherche (CIR) accreditation from the French Ministère de la Recherche for the period 2017-2020, then renewed for 2020-2022 period, and now for 2022-2025 period, promoting partnership between companies on Research and Development oriented projects.

How to get started?


You contact us by email or by phone.


We review your project and scientific background information.


We create a detailed project proposal, tailored to your needs.

About Us


Calvagone was founded by Christian Laveille and rapidly several consultants joined the company. Since February 2024, leadership is assumed by Emilie, Andreas and Erno. We are growing!

What defines us: Enthusiasm, Flexibility, Solid Expertise and Keenness to Establish Long-Term Relationships.



What to do first, when we want to work with Calvagone?

The first thing to do is to put a mutual non-disclosure-agreement in place using either your or our own template.

How much do your services cost?

Every project is unique and highly customized. Please contact us for a detailed proposal. Note, we do offer discounts for new clients.

Are you invoicing based on the time spent on the project?

It depends, we usually prefer to define a milestone-based quotation, where each milestone is clearly described regarding timelines and costs. There are no hidden costs. However, for general consulting projects, we invoice based on the time spent.

Where are you located?

We are working from home, and are located in France, in the Netherlands, in Spain, in Belgium and in Finland. The official address is in France (see our contact details).

Do you have the capability to run compute-intensive PK/PD models?

Yes, we have set-up a high-performance computing server, which is hosted near Lyon in a dedicated datacentre. We have already run some very complex PK/PD models in a reasonable time.

Do you have some Standard Operating Procedures in place?

Yes, we have SOPs for the key aspects of our work. As we are working from home, it is really important to have standardization in order to achieve efficiency and uniformity of performance.

Do you have specific accreditations?

Yes, we obtained in April 2017 the accreditation for Crédit Impôt Recherches (CIR) from the French « Ministère de la Recherche » for a three-year period. This accreditation has been renewed in 2020 and in 2022, presently active until 2025.